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Enalapril-Hydrochlorothiazide is a combination medication that’s used to treat high blood pressure (hypertension). Enalapril helps relax blood vessels. Hydrochlorothiazide is a diuretic (“water pill”) that tells the body to urinate (pee) more. This lowers the fluid and salt levels in blood vessels. Together, these medicines help blood pressure go down. Vaseretic is the brand version of this medication.
Please note: At this time, this medication is only prescribed as a refill at Dr. B.
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How Dr. B treats high blood pressure
Tell us about your condition with a $15 online consultation—no video call necessary.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Vaseretic (Enalapril-Hydrochlorothiazide)
How does it work?
Vaseretic is a hypertension medication that combines two different drugs: Enalapril and Hydrochlorothiazide. Enalapril is an angiotensin converting enzyme (ACE) inhibitor that relaxes blood vessels. Hydrochlorothiazide is a diuretic (“water pill”) that helps the body eliminate extra salt and water by urinating more. This combination helps reduce the workload on the heart.
What does it treat?
This medicine helps lower blood pressure. It can also protect the kidneys and reduce the risk of heart attack, stroke and other related problems.
What forms does it come in?
This blood pressure medicine comes as a tablet that’s taken by mouth. It combines two medicines in one pill for convenient dosing.
Vaseretic vs. Enalapril-Hydrochlorothiazide
Vaseretic and Enalapril-Hydrochlorothiazide are essentially the same medication. Enalapril-Hydrochlorothiazide is the generic version of this combination drug. Both contain Enalapril (an ACE inhibitor) and Hydrochlorothiazide (a diuretic), which work together to lower blood pressure.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Enalapril 5 mg-Hydrochlorothiazide 12.5 mg (30 tablets) start at $8.33.
* Prices shown with drug discount card applied. Price may differ depending on location.
Enalapril 5 mg-Hydrochlorothiazide 12.5 mg (30 tablets)*
More High Blood Pressure (Hypertension) Prescription Refills
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Common Questions
Vaseretic (Enalapril-Hydrochlorothiazide) prescription FAQ
What are the benefits of taking Vaseretic (Enalapril-Hydrochlorothiazide)?
- Lowers blood pressure
- Reduces swelling caused by fluid buildup
- Combines two effective medications
- Convenient once-daily dosing
- Reduces risk of heart attack and stroke
- Protects kidney function
Who should not take this medication?
- Those who are allergic to Enalapril or Hydrochlorothiazide
- People with a known allergy or severe reaction to ACE inhibitors, diuretics or sulfonamide-derived drugs
- Pregnant women, breastfeeding or those planning to become pregnant
- Those with specific heart valve conditions
- People with a history of gout
- Those who have low blood pressure (hypotension)
- People with a history of angioedema (swelling of the face, lips, tongue or throat)
- People with a rare genetic condition called hereditary angioedema
- Those with severe kidney disease or a history of kidney problems
- People who have high levels of potassium in the blood (hyperkalemia)
- Those who are taking Neprilysin Inhibitors like Entresto (Sacubitril/Valsartan)
- People who are taking Aliskiren, another type of blood pressure medication
- People with a history of electrolyte imbalances, as diuretics can cause imbalances in potassium, sodium, magnesium, and chloride levels in the blood
If you have any of these conditions—or a history of dehydration, Marfan's disease or Ehler's Danlos disease, heart failure, diabetes, liver problems, adrenal gland problems, primary aldosteronism (a condition that causes the adrenal glands to produce too much aldosterone, a hormone that helps regulate blood pressure), or collagen vascular disease (such as lupus or scleroderma)—speak with your healthcare provider before starting this medication.
Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.
Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.
How do you take this medication?
Take this medicine as directed by your health provider, usually once or twice a day. It’s best to take this medicine in the morning. If you take it close to bedtime, you might have to get up to use the bathroom during the night.
High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.
Also, please keep in mind that it may take some time for this medication to achieve its full effect in managing your blood pressure. Don't be discouraged if you don't notice immediate changes. Continue taking your medication as prescribed, and consult with your healthcare provider if you have any questions or concerns.
What happens if I miss a dose?
If you miss a dose of your blood pressure medicine, just take it as soon as you remember. But if it’s almost time for your next dose, just skip it. Don’t double the dose to make up for the missed dose.
What happens if I take too much?
Taking too much of your hypertension medicine can lead to serious problems like low blood pressure, excessive urination and electrolyte imbalances.
If you’ve taken too much Vaseretic, call your medical provider or local poison control center (800-222-1222) immediately.
Can I get Vaseretic (Enalapril-Hydrochlorothiazide) online?
Need a refill for your blood pressure medication? Dr. B can help! Just complete a virtual consultation to connect with a licensed medical provider. They’ll review your health history and, if appropriate, send an online refill to your preferred pharmacy.
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Side Effects
It’s possible to experience side effects while using this medicine. You might notice:
- Headache
- Dizziness or lightheadedness
- Dry cough
- Tiredness
- Muscle cramps
- Diarrhea
- Dehydration
If your side effects bother you, or if you have any other concerns, let your health provider know right away. Also keep an eye out for signs of a more serious reaction that needs immediate attention. This might include severe swelling that occurs beneath the skin–most commonly in the face, lips, tongue, or throat (angioedema), yellowing skin or eyes, not peeing as much or a skin rash.
This medication, along with its component hydrochlorothiazide (HCTZ), can potentially alter serum potassium levels, so it’s important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.
Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.