Get an Avalide (Irbesartan-Hydrochlorothiazide) prescription online

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Irbesartan-Hydrochlorothiazide is used to treat high blood pressure (hypertension). It's a combination medication that helps relax blood vessels and remove extra fluid by increasing urination. It only needs to be taken once a day. Avalide is the brand name.

Please note: At this time, this medication is only prescribed as a refill at Dr. B.

* Prescription treatment requires a virtual medical consultation with a medical provider to determine if a prescription is appropriate.

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How Dr. B treats high blood pressure

1
Health assessment

Tell us about your condition with a $15 online consultation—no video call necessary.

2
Provider review

A medical provider will review your information and prescribe treatment, if appropriate.

3
Get your medication

Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.

About Avalide (Irbesartan-Hydrochlorothiazide)

How does it work?

Avalide contains two medicines that work together to lower blood pressure. Irbesartan is an angiotensin II receptor blocker (ARB). It helps relax blood vessels so more oxygen and blood reach the heart. Hydrochlorothiazide is a diuretic (“water pill”) that tells your body to urinate more. This helps remove extra water and salts from the bloodstream. Together, these medicines reduce the workload on the heart and lower blood pressure.

What does it treat?

This medication is used to treat hypertension (high blood pressure). Treating high blood pressure can lower the risk of heart attack, stroke, kidney failure and other problems that affect your blood vessels.

What forms does it come in?

This hypertension medicine comes as a tablet that’s taken by mouth.

Avalide vs. Irbesartan-Hydrochlorothiazide

These are the same medications. Avalide is just a brand-name version. Brands and generics contain the same active ingredients and work the same way to lower blood pressure. Different brands might have slightly different packaging or contain other ingredients, too. Your licensed provider can help you know which version is right for you.

How much will it cost?

Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Avalide 150 mg-12.5 mg (30 tablets) start at $33.64.

* Prices shown with drug discount card applied. Price may differ depending on location.

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$15
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Starting at
$33.64
$293.72
$295.89
$297.73
$11.70

Avalide 150 mg-12.5 mg (30 tablets)*

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Common Questions

Avalide (Irbesartan-Hydrochlorothiazide) prescription FAQ

What are the benefits of taking Avalide (Irbesartan-Hydrochlorothiazide)?
  • Lowers blood pressure
  • Reduces the risk of stroke
  • Reduces the risk of heart attack or heart problems
  • Protects the kidneys
  • Contains two medications in one
  • Convenient once-daily dosing
Who should not take this medication?
  • Those who are allergic to Irbesartan or Hydrochlorothiazide
  • People with a known allergy or severe reaction to ARBs (Angiotensin II Receptor Blockers), diuretics or sulfonamide-derived drugs
  • Pregnant women, breastfeeding or those planning to become pregnant
  • People with a history of gout
  • People with a history of angioedema (swelling of the face, lips, tongue or throat)
  • People with a rare genetic condition called hereditary angioedema
  • Those with severe kidney disease or a history of kidney problems
  • People who have high levels of potassium in the blood (hyperkalemia)
  • Those who are taking Neprilysin Inhibitors like Entresto (Sacubitril/Valsartan)
  • People who are taking Aliskiren, another type of blood pressure medication
  • People with a history of electrolyte imbalances, as diuretics can cause imbalances in potassium, sodium, magnesium, and chloride levels in the blood

If you have any of these conditions—or a history of dehydration, heart failure, diabetes, liver problems, adrenal gland problems, primary aldosteronism (a condition that causes the adrenal glands to produce too much aldosterone, a hormone that helps regulate blood pressure), or collagen vascular disease (such as lupus or scleroderma)—speak with your healthcare provider before starting this medication.

Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.

Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.

How do you take this medication?

Avalide is usually taken by mouth once a day, with or without food. This medicine makes you urinate (pee) more often. Take this medicine in the morning to avoid needing to get up at night to use the bathroom.

High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.

Also, please keep in mind that it may take some time for this medication to achieve its full effect in managing your blood pressure. Don't be discouraged if you don't notice immediate changes. Continue taking your medication as prescribed, and consult with your healthcare provider if you have any questions or concerns.

What happens if I miss a dose?

If you miss a dose of your blood pressure medicine, take it as soon as you remember. But if it’s almost time for the next dose, just skip it and continue with your regular dosing schedule. Don’t take more than your normal dose to catch up.

What happens if I take too much?

Taking too much of this hypertension medicine can lead to problems like dehydration and irregular heartbeat.

If you’ve taken too much Avalide, call your licensed medical provider or local poison control center (800-222-1222) immediately.

Can I get Avalide (Irbesartan-Hydrochlorothiazide) online?

Dr. B can help you get a convenient, online refill for your hypertension medications, including Avalide and Irbesartan-Hydrochlorothiazide. Just fill out a short health questionnaire to start the process.

Dr. Sudip Bose

Medical information reviewed by Dr. Sudip Bose

Sudip Bose, MD is a world-leading emergency medicine physician, combat veteran, professor, and entrepreneur. With a wide variety of experience, Dr. Bose is focused on endeavors with large-scale health and educational impact. He founded The Battle Continues, a nonprofit assisting veterans with healthcare needs. Dr. Bose is also a clinical professor at Texas Tech and University of Illinois College of Medicine. He is a graduate of the honors program at Northwestern University, where he continued his medical school education at The Feinberg School of Medicine.

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Side Effects

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Irbesartan-Hydrochlorothiazide is generally well-tolerated and most people only experience mild side effects. The most common side effects are:

  • Dizziness
  • Muscle pain
  • Fatigue
  • Nausea or vomiting
  • Muscle cramps
  • Dehydration
  • Dry cough

Alert your health provider right away if you experience more serious side effects, like swelling in your legs or hands, confusion or problems urinating. If you have problems breathing, swelling of the face or tongue or irregular heartbeat, get emergency help immediately.

This medication, along with its component hydrochlorothiazide (HCTZ), can potentially alter serum potassium levels, so it’s important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.

Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.