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Chlorthalidone is used to treat high blood pressure (hypertension). This medicine is a diuretic (“water pill”) that helps the kidneys remove extra water and salt, which lowers blood pressure. Controlling blood pressure levels can help prevent heart failure, kidney disease and damage to the blood vessels. The brand version is Thalitone.
Please note: At this time, this medication is only prescribed as a refill at Dr. B.
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How Dr. B treats high blood pressure
Tell us about your condition with a $15 online consultation—no video call necessary.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
How does it work?
Chlorthalidone is a medication known as a diuretic or “water pill.” It works by telling the kidneys to release more urine and electrolytes. By helping the body remove excess salt and water, it reduces the amount of fluid in blood vessels. This lowers blood pressure and decreases the workload on the heart.
What does it treat?
Chlorthalidone is primarily used to treat high blood pressure (hypertension). It also helps reduce swelling (edema) for people with conditions like heart failure, liver problems or kidney problems. Managing blood pressure also reduces the risk of heart attack, stroke, kidney problems or vision loss.
What forms does it come in?
This hypertension medicine comes as a tablet that’s taken by mouth.
Chlorthalidone vs. Thalitone
Chlorthalidone and Thalitone are actually the same medication. Thalitone is just a brand name version of this diuretic drug. They both help the body remove excess salt and water to lower blood pressure.
The brand drug Thalitone is not currently available on the Dr. B platform.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Chlorthalidone 25 mg (30 tablets) start at $2.54.
* Prices shown with drug discount card applied. Price may differ depending on location.
Chlorthalidone 25 mg (30 tablets)*
More High Blood Pressure (Hypertension) Prescription Refills
Looking for a different hypertension medication? Here are some options.
Chlorthalidone prescription FAQ
What are the benefits of taking Chlorthalidone?
- Lowers blood pressure
- Reduces swelling caused by fluid buildup
- Decreases risk of stroke and heart attack
Who should not take this medication?
- Those who are allergic to Chlorthalidone
- People with a known allergy or severe reaction to diuretics or sulfonamide-derived drugs
- Those who have experienced severe skin reactions while taking diuretics
- Pregnant women, breastfeeding or those planning to become pregnant
- People with a history of gout
- Those with severe kidney disease or a history of kidney problems
- People with severe liver disease or a history of liver problems
- People who have high levels of potassium in the blood (hyperkalemia)
- People with a history of electrolyte imbalances, as diuretics can cause imbalances in potassium, sodium, magnesium, and chloride levels in the blood
If you have any of these conditions—or a history of dehydration, lupus or other autoimmune diseases, heart failure, adrenal gland problems, or collagen vascular disease (such scleroderma)—speak with your healthcare provider before starting this medication.
Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.
Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.
How do you take this medication?
Take this medicine by mouth, usually once daily or every other day. It's best to take this medicine in the morning. That will keep you from having to get up at night to use the bathroom.
High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.
What happens if I miss a dose?
If you miss a dose of your hypertension pill, take it as soon as you remember. If it's close to the time for your next dose, skip the missed one. Do not double the dose to make up for the missed one.
What happens if I take too much?
Taking too much of your blood pressure medicine can lead to symptoms like excessive urination, dehydration, low blood pressure and electrolyte imbalances.
If you’ve taken too much Chlorthalidone, call your healthcare provider or local poison control center (800-222-1222) immediately.
Can I get Chlorthalidone online?
Yes! Just complete an online consultation with Dr. B. A licensed medical provider will review your health history. If appropriate, they will send a refill to your pharmacy of choice.
Medical information reviewed by Dr. Sudip Bose
Sudip Bose, MD is a world-leading emergency medicine physician, combat veteran, professor, and entrepreneur. With a wide variety of experience, Dr. Bose is focused on endeavors with large-scale health and educational impact. He founded The Battle Continues, a nonprofit assisting veterans with healthcare needs. Dr. Bose is also a clinical professor at Texas Tech and University of Illinois College of Medicine. He is a graduate of the honors program at Northwestern University, where he continued his medical school education at The Feinberg School of Medicine.
Some people experience side effects while using this medicine. The most common side effects are:
- Sensitivity to the sun
- Nausea or vomiting
- Worsening gout
- Temporary muscle pain/weakness
- Stomach cramps
- Muscle cramps
Tell your health provider if your symptoms bother you or if you have any concerns. Also watch for signs of a more serious problem, like breathing problems, swelling of the face or tongue, not urinating as much, rash or any other unusual skin reactions, muscle weakness or yellowing skin/eyes.
Chlorthalidone is a diuretic (“water pill”) which can potentially lower serum potassium levels, so it’s important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.
Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.