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Lotrel helps lower blood pressure and reduce the risk of heart problems. This hypertension treatment combines two blood pressure medications: Amlodipine and Benazepril. Lotrel works best when combined with a healthy diet and exercise plan. It’s also available as a generic (Amlodipine-Benazepril).
Please note: At this time, this medication is only prescribed as a refill at Dr. B.
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How Dr. B treats high blood pressure
Tell us about your condition with a $15 online consultation—no video call necessary.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Lotrel (Amlodipine-Benazepril)
How does it work?
Lotrel combines two drugs that work together to lower blood pressure. Amlodipine is a calcium-channel blocker. It helps relax blood vessels so the heart doesn’t have to work as hard to pump blood. Benazepril helps relax blood vessels so blood flows more smoothly. It’s known as an angiotensin-converting enzyme (ACE) inhibitor. That means that it works by blocking the production of ACE proteins that make blood vessels squeeze tighter.
What does it treat?
This hypertension medicine helps lower blood pressure. This reduces the risk of heart problems like stroke, heart attack, heart failure, heart disease and kidney failure. It works best when used alongside a healthy diet and exercise program.
What forms does it come in?
Lotrel is typically available as a capsule that’s taken by mouth. It’s usually taken once a day.
Lotrel vs. Amlodipine-Benazepril
Lotrel is a brand name medication that contains both Amlodipine and Benazepril. Amlodipine-Benazepril is a generic version of the same combination. Both brand and generic versions work the same way to control high blood pressure.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Amlodipine 5 mg-Benazepril 10 mg (30 capsules) start at $12.18.
* Prices shown with drug discount card applied. Price may differ depending on location.
Amlodipine 5 mg-Benazepril 10 mg (30 capsules)*
More High Blood Pressure (Hypertension) Prescription Refills
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Lotrel (Amlodipine-Benazepril) prescription FAQ
What are the benefits of taking Lotrel (Amlodipine-Benazepril)?
- Lowers blood pressure
- Reduces risk of heart attack and stroke
- Improves blood flow to the heart
- Makes it easier for the heart to pump blood
- Reduces the risk of kidney disease
- Lowers the risk of vision problems related to high blood pressure
Who should not take this medication?
- Those who are allergic to Amlodipine, Benazepril or any other ACE inhibitor
- Pregnant women, breastfeeding or those planning to become pregnant
- People with severe heart conditions or heart failure
- People who have slow heart rate (bradycardia)
- Those with low blood pressure (hypotension)
- Those with myasthenia gravis (muscle disorder)
- People with sick sinus syndrome (a heart rhythm problem)
- Those who have second- or third-degree atrioventricular block (a heart rhythm problem)
- People with a history of angioedema (swelling of the face, lips, tongue or throat)
- People with a rare genetic condition called hereditary angioedema
- Those with severe kidney disease or a history of kidney problems
- People who have high levels of potassium in the blood (hyperkalemia)
- Those with specific heart valve conditions
- Those who are taking Neprilysin Inhibitors like Entresto (Sacubitril/Valsartan)
- People who are taking Aliskiren, another type of blood pressure medication
If you have any of these conditions—or history of dehydration, Raynaud's syndrome (a condition that causes the fingers and toes to become numb and cold), asthma, other respiratory issues, a history of significant lung diseases, porphyria (a rare blood disorder), liver or kidney complications, low blood pressure (hypotension) or Collagen vascular disease (such as lupus or scleroderma), or diabetes—speak with your healthcare provider before starting this medication.
Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.
Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.
How do you take this medication?
Lotrel is taken by mouth, once a day, with or without food. Follow your medical provider’s instructions carefully to make sure you use this medicine safely.
High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.
Also, please keep in mind that it may take some time for this medication to achieve its full effect in managing your blood pressure. Don't be discouraged if you don't notice immediate changes. Continue taking your medication as prescribed, and consult with your healthcare provider if you have any questions or concerns.
What happens if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's close to the next scheduled dose, skip the missed one. Never take two doses at the same time to catch up.
What happens if I take too much?
Taking too much Lotrel can cause serious side effects like extremely low blood pressure, hyperglycemia (high blood sugar), dizziness and rapid heartbeat. If you suspect an overdose, seek medical attention immediately.
If you’ve taken too much Lotrel, call your licensed provider or local poison control center (800-222-1222) immediately.
Can I get Lotrel (Amlodipine-Benazepril) online?
If you need a prescription for hypertension medicine–including Lotrel–Dr. B has you covered. Just complete an online health questionnaire about your health history. A licensed medical provider will work with you on a treatment plan to help you manage your hypertension.
Medical information reviewed by Dr. Sudip Bose
Sudip Bose, MD is a world-leading emergency medicine physician, combat veteran, professor, and entrepreneur. With a wide variety of experience, Dr. Bose is focused on endeavors with large-scale health and educational impact. He founded The Battle Continues, a nonprofit assisting veterans with healthcare needs. Dr. Bose is also a clinical professor at Texas Tech and University of Illinois College of Medicine. He is a graduate of the honors program at Northwestern University, where he continued his medical school education at The Feinberg School of Medicine.
It’s possible to have some mild side effects while using this medicine, including:
- Dizziness or lightheadedness
- Flushing (feeling warm)
- Dry cough
- Swelling of arms, legs, hands or feet
Call your health provider immediately if you experience severe side effects like chest pain or tightness, a severe swelling or swelling that occurs beneath the skin–most commonly in the face, lips, tongue, or throat (angioedema), urinating less often than usual, nausea or abnormal heartbeat, dizziness or feeling faint, confusion or yellowing skin/eyes. If you notice any of these symptoms, or anything else that concerns you, get help right away.
Don’t drive until you know how this medicine affects you. Be extra careful in the first hours after taking your pill because of the risk of dizziness or lightheadedness.
This medication can potentially increase serum potassium levels, so it's important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.
Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.