Get a Hyzaar (Losartan-Hydrochlorothiazide) prescription online

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Hyzaar is the brand version of Losartan-Hydrochlorothiazide—a combination tablet for treating high blood pressure (hypertension). Losartan is an angiotensin II receptor blocker (ARB), which relaxes blood vessels to lower blood pressure. Hydrochlorothiazide is a diuretic that triggers urination, which removes excess water and electrolytes from the body.

Please note: At this time, this medication is only prescribed as a refill at Dr. B.

* Prescription treatment requires a virtual medical consultation with a medical provider to determine if a prescription is appropriate.

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How Dr. B treats high blood pressure

Health assessment

Tell us about your condition with a $15 online consultation—no video call necessary.

Provider review

A medical provider will review your information and prescribe treatment, if appropriate.

Get your medication

Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.

About Hyzaar (Losartan-Hydrochlorothiazide)

How does it work?

Hyzaar relaxes blood vessels and reduces the amount of water in the body. This lowers the blood pressure, which makes it easier for the heart to pump blood.

What does it treat?

This combination hypertension medicine treats high blood pressure—which happens when the force of blood against the walls of your arteries gets too high. It is also sometimes prescribed to help protect the kidneys in people with type 2 diabetes who have high blood pressure.

What forms does it come in?

This hypertension treatment comes in the form of tablets you take by mouth. These tablets contain two medications—Losartan and Hydrochlorothiazide—combined in one pill to help treat people with high blood pressure.

Hyzaar vs. Losartan-Hydrochlorothiazide

Hyzaar and Losartan-Hydrochlorothiazide are the same medications. Hyzaar is a brand-name version of the two drugs, Losartan and Hydrochlorothiazide. They work the same way and treat the same conditions. But they may have different names (depending on the manufacturer).

How much will it cost?

Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Losartan 50 mg-Hydrochlorothiazide 12.5 mg (30 tablets) start at $4.00.

* Prices shown with drug discount card applied. Price may differ depending on location.

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Starting at

Losartan 50 mg-Hydrochlorothiazide 12.5 mg (30 tablets)*

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Common Questions

Hyzaar (Losartan-Hydrochlorothiazide) prescription FAQ

What are the benefits of taking Hyzaar (Losartan-Hydrochlorothiazide)?
  • Lowers blood pressure
  • Reduces stroke and heart attack risk
  • Protects blood vessels from damage
  • Improves heart function
  • Slows progression of kidney disease
Who should not take this medication?
  • People who are allergic to Losartan or Hydrochlorothiazide
  • People with a known allergy or severe reaction to ARBs (Angiotensin II Receptor Blockers), diuretics or sulfonamide-derived drugs
  • Pregnant women, breastfeeding or those planning to become pregnant
  • People with a history of gout
  • People with a history of angioedema (swelling of the face, lips, tongue or throat)
  • People with a rare genetic condition called hereditary angioedema.
  • Those with severe kidney disease or a history of kidney problems.
  • People who have high levels of potassium in the blood (hyperkalemia).
  • Those who are taking Neprilysin Inhibitors like Entresto (Sacubitril/Valsartan)
  • People who are taking Aliskiren, another type of blood pressure medication
  • People with a history of electrolyte imbalances, as diuretics can cause imbalances in potassium, sodium, magnesium, and chloride levels in the blood

If you have any of these conditions—or a history of dehydration, heart failure, diabetes, liver problems, adrenal gland problems, primary aldosteronism (a condition that causes the adrenal glands to produce too much aldosterone, a hormone that helps regulate blood pressure), or collagen vascular disease (such as lupus or scleroderma)—speak with your healthcare provider before starting this medication.

Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.

Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.

How do you take this medication?

You take this medication by mouth, with or without food, usually once daily, as directed by your licensed medical provider. As it may increase urination, taking it at least 4 hours before bedtime is often recommended. But follow your health provider’s specific instructions for the best results.

High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.

Also, please keep in mind that it may take some time for this medication to achieve its full effect in managing your blood pressure. Don't be discouraged if you don't notice immediate changes. Continue taking your medication as prescribed, and consult with your healthcare provider if you have any questions or concerns.

What happens if I miss a dose?

If you miss a dose, take it as soon as you remember—unless the time is close to your next dose. If that's the case, skip the missed dose. Don't take extra medicine to make up for what you’ve missed.

What happens if I take too much?

Taking too much of this medication can lead to symptoms like dizziness, rapid heartbeat and excessive urination. If you suspect you’ve taken too much, immediately call your medical provider or local poison control center (800-222-1222).

Can I get Hyzaar (Losartan-Hydrochlorothiazide) online?

Right now, our online consultation services can only help you get hypertension medication refills. Dr. B can’t help you get an initial hypertension prescription.

If you’ve already been diagnosed with hypertension and prescribed medication, our hassle-free, $15 online consultations can help you keep your prescription filled. We don’t require an in-office visit or phone appointment. This makes Dr. B an affordable and convenient way to keep your medication stocked up.

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Side Effects

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Not everyone will experience side effects when taking this medication. When they do happen, they’re often mild and can include:

  • Dizziness
  • Cough
  • Lightheadedness
  • Muscle cramps
  • Dehydration
  • Dry cough

Immediately contact your health provider if you experience symptoms of dehydration or an electrolyte imbalance. These can include a very dry mouth, extreme thirst, muscle cramps, a changed heart rhythm or confusion.

In rare cases, this medication may trigger swelling of the neck, throat, tongue or lips (angioedema). Black patients and those with a family history of angioedema are at higher risk. To reduce the risk of severe complications, share your complete health history and potential drug interactions with your medical provider.

This medication, along with its component hydrochlorothiazide (HCTZ), can potentially alter serum potassium levels, so it’s important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.

Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.