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Hydrochlorothiazide is used to treat high blood pressure (hypertension). It’s a diuretic (“water pill”) that helps the body urinate (pee) more often. This removes extra water and salt from the body, which can help lower blood pressure. Hydrochlorothiazide may also help reduce some kinds of swelling.
Please note: At this time, this medication is only prescribed as a refill at Dr. B.
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How Dr. B treats high blood pressure
Tell us about your condition with a $15 online consultation—no video call necessary.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Hydrochlorothiazide
How does it work?
Hydrochlorothiazide is a thiazide diuretic. Some people call it a water pill. It tells your kidneys to make more urine, which helps remove extra water and electrolytes from the body. This helps lower blood pressure and reduce swelling in conditions like edema.
What does it treat?
Hydrochlorothiazide is used to treat high blood pressure (hypertension). It also reduces excess fluid in the body (edema) caused by conditions like heart failure, kidney problems or liver conditions.
What forms does it come in?
This hypertension medicine is taken by mouth. It comes as a tablet, capsule or liquid solution.
Please note that Hydrochlorothiazide liquid solution is not listed among the available options on the Dr. B platform at this time.
Hydrochlorothiazide vs. Microzide
Hydrochlorothiazide and Microzide are actually the same medication; Microzide is just a brand name for Hydrochlorothiazide. They both work the same way to remove unneeded water and salt in the body.
The brand drug Microzide is not currently available on the Dr. B platform.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a high blood pressure prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Hydrochlorothiazide 25 mg (30 tablets) start at $1.79.
* Prices shown with drug discount card applied. Price may differ depending on location.
Hydrochlorothiazide 25 mg (30 tablets)*
More High Blood Pressure (Hypertension) Prescription Refills
Looking for a different hypertension medication? Here are some options.
Common Questions
Hydrochlorothiazide prescription FAQ
What are the benefits of taking Hydrochlorothiazide?
- Lowers blood pressure
- Reduces swelling caused by fluid buildup
- Reduces risk of complications like heart attack and stroke
- Protects kidney function
Who should not take this medication?
- Those who are allergic to Hydrochlorothiazide
- People with a known allergy or severe reaction to diuretics or sulfonamide-derived drugs
- Those who have experienced severe skin reactions while taking diuretics
- Pregnant women, breastfeeding or those planning to become pregnant
- People with a history of gout
- Those with severe kidney disease or a history of kidney problems
- People with severe liver disease or a history of liver problems
- People who have high levels of potassium in the blood (hyperkalemia)
- People with a history of electrolyte imbalances, as diuretics can cause imbalances in potassium, sodium, magnesium, and chloride levels in the blood
If you have any of these conditions—or a history of dehydration, lupus or other autoimmune diseases, heart failure, adrenal gland problems, or collagen vascular disease (such scleroderma)—speak with your healthcare provider before starting this medication.
Taking this medication when you have these conditions should be carefully and closely monitored by a healthcare provider.
Also tell your medical provider about any other medications you’re using before you start this hypertension treatment.
How do you take this medication?
This medicine is taken once or twice a day, as directed by your licensed provider. It starts working about two hours after you swallow it. Take it in the morning so you don’t have to use the bathroom frequently overnight.
High blood pressure is a long-term (chronic) condition that can harm your organs. Medications for blood pressure are not a one-time cure. This medicine doesn't provide a complete cure for high blood pressure, so it's important to continue taking it, even if you start feeling better. If you stop taking it suddenly, this could cause dangerous problems, like heart attack or stroke. Follow your medical provider's instructions carefully.
What happens if I miss a dose?
It’s important to take your blood pressure medicine exactly as prescribed. If you miss a dose, take it as soon as you can. Just don’t take two close together or at the same time. If it’s almost time for your next dose, skip the missed dose.
What happens if I take too much?
Taking too much of your blood pressure medicine can lead to symptoms like extreme thirst, confusion and muscle pain.
If you’ve taken too much Hydrochlorothiazide, call your medical provider or local poison control center (800-222-1222) immediately.
Can I get Hydrochlorothiazide online?
Dr. B offers convenient, virtual consultations to help you get refills for your blood pressure medications. Just complete a short health questionnaire to get started. A licensed medical provider will review your health history to see if an online prescription is right for you.
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Side Effects
If you have side effects that bother you, let your medical provider know right away. The most common side effects are:
- Dizziness or lightheadedness
- Headache
- Sun sensitivity
- Weakness
- Loss of appetite
- Diarrhea, nausea or vomiting
- Frequent urination
- Unbalanced electrolyte levels
- Muscle cramps
- Dehydration
Talk to your health provider if your side effects are bothering you or if they don’t get better. Get emergency help right away if your symptoms are more severe. This could include signs of an allergic reaction (skin peeling, rash or trouble breathing) or pancreas problems (pain or tenderness in the stomach, fever, nausea or vomiting).
Hydrochlorothiazide (HCTZ) is a diuretic (“water pill”) which can potentially lower serum potassium levels, so it’s important to keep an eye on your potassium levels when taking this medication. It's best to consult a healthcare provider for routine checks. It's a simple step that can help ensure your treatment's effectiveness and safety.
Getting your blood tested regularly is important to monitor your overall health. It's a good idea to have your bloodwork checked, which may include tests for renal function, glucose levels or potassium levels in your blood. These routine checks help ensure you are in good health and catch any potential issues early.