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Rhofade is a brand-name medication that reduces redness caused by rosacea. It works by narrowing blood vessels in your skin. The active ingredient in this rosacea medicine is called Oxymetazoline. There’s no generic version available, so it can be expensive depending on your insurance.
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How Dr. B treats rosacea
Tell us about your condition with a $15 online consultation—no video call necessary.
A medical provider will review your information and prescribe treatment, if appropriate.
Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.
About Oxymetazoline (Generic Rhofade)
How does it work?
Rhofade works by shrinking blood vessels near the skin surface. This helps reduce redness and swelling so skin looks less irritated and more even-toned.
What does it treat?
This rosacea medicine treats redness and swelling from rosacea. The active ingredient, Oxymetazoline (brand name: Afrin), is also found as a nasal spray for congestion.
What forms does it come in?
This rosacea treatment is available as a cream that you apply directly to the affected area of your face. It comes in a tube or convenient pump bottle.
Oxymetazoline vs. Rhofade
Oxymetazoline is the active ingredient in Rhofade. Rhofade is a brand-name medication. There’s no generic version of this rosacea treatment, so it can be expensive depending on the type of insurance you have.
How much will it cost?
Dr. B offers online consultations for $15—which is less than most copays. If a rosacea prescription is appropriate, your out-of-pocket medication cost will depend on your insurance and where you decide to get your prescription filled. With a drug discount card, prices for Rhofade 1 % Topical Cream (30 gram tube) start at $585.92.
* Prices shown with drug discount card applied. Price may differ depending on location.
Rhofade 1 % Topical Cream (30 gram tube)*
More Rosacea Prescription Treatments
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Oxymetazoline (Generic Rhofade) prescription FAQ
What are the benefits of using Oxymetazoline (Generic Rhofade)?
- Reduces skin redness and swelling
- Improves skin appearance
- Treats rosacea
- Relieves inflammation
Who should not use this medication?
- People who are allergic to it or any of its ingredients
- People who have glaucoma
- People who have heart problems, such as high blood pressure or heart disease
- People with circulation issues, like Reynaud’s disease or a history of stroke
- People who are pregnant or breastfeeding
- People who take certain medications
This medication affects your blood vessels, so it can be dangerous for people with certain medical conditions or who take some kinds of medication. It can also dangerously affect blood pressure, especially in people who have a history of high blood pressure.
Take this medicine exactly as prescribed and let your licensed provider know your full medical history, including any other medications you use, before starting this treatment.
How do I use this medication?
Apply a pea-sized amount of cream to your nose, forehead, cheeks or chin. Don’t use it anywhere else on your body, and avoid getting it in your eyes or mouth. Wash your hands after using this medicine to avoid unwanted side effects.
What happens if I miss a dose?
If you miss a dose, simply apply it as soon as you remember. Just don't use extra to make up for the missed dose.
What happens if I use too much?
Using too much of this medicine can lead to side effects like itching or irritation as well as circulation problems. It's essential to follow your medical provider's instructions carefully when using this medicine.
If you’ve used too much Rhofade, call your healthcare provider or local poison control center (800-222-1222) immediately.
Can I get Oxymetazoline (Generic Rhofade) online?
If you’re struggling with redness from rosacea, Dr. B has solutions. Fill out a short health questionnaire about your symptoms, and Dr. B will connect you with a licensed medical provider who can recommend the right treatment for your rosacea. If appropriate, they can even send a prescription directly to the pharmacy of your choice.
Medical information reviewed by Dr. Alison Gruen
Alison Gruen, MD is a board-certified dermatologist in New York City with over 18 years of experience. A clinician at heart, she happily devotes most of her time to the care of her patients. She graduated Magna Cum Laude from Princeton University and received her MD degree from the Yale School of Medicine. Dr. Gruen completed her dermatology residency at SUNY Downstate where she served as Chief Resident and was awarded the Kings County Doctor’s Day award for compassion in medicine. Currently Dr. Gruen is affiliated with Mount Sinai Hospital in Manhattan.
This medicine can cause side effects for some people. Mild side effects might include:
- Skin redness
- Pain where applied
- Worsening rosacea symptoms
It’s important to watch for serious side effects while using this medicine. If you notice symptoms like chest pain, dizziness, shortness of breath, leg swelling or changes in vision, talk to your health provider or get emergency help right away.