Vtama

Tapinarof Vtama (the brand version of Tapinarof) is a medication used to treat plaque psoriasis. It's an aryl hydrocarbon receptor agonist thought to reduce inflammation by stimulating the AhR protein. The medication is applied as a cream. Read more about psoriasis.
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How to use this information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective or appropriate for you. This information is not individual medical advice and does not substitute for the advice of a medical provider. If you have any questions, go to your patient dashboard and request a callback for complete information about this product and your specific health needs.
Medication name: 

TAPINAROF - TOPICAL

(ta-PIN-ar-of)

COMMON BRAND NAME(S): VTAMA

What you should know about Tapinarof

This medication is used to treat a skin condition called plaque psoriasis. Tapinarof can help lessen symptoms like red, scaly patches of skin.

How to take Tapinarof
  • Read the Patient Information Leaflet if available from your pharmacist before you start using Tapinarof and each time you get a refill. If you have any questions, ask your medical provider or pharmacist.
  • Wash and dry your hands before applying the medication, then clean and dry the affected area. Apply a thin film of the medication to the affected area and gently rub in as directed by your medical provider, usually once daily. Do not apply this medication to normal, healthy skin. 
  • Wash your hands after using this medication unless your hands are being treated. If your medical provider recommends a moisturizer, apply it after this medication.
  • This medication is for use on the skin only. Avoid getting this medication in your eyes, mouth or vagina. If you do get the medication in those areas, flush with plenty of water.
  • Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day.
  • Do not use large amounts, apply this medication more often than directed or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. 
  • Tell your medical provider if your condition does not get better or gets worse.
Potential side effects
  • Skin irritation/redness or small red bumps on the skin (folliculitis) may occur where the medication is applied. If any of these effects last or get worse, tell your medical provider or pharmacist right away.
  • Remember that this medication has been prescribed because your medical provider has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not experience serious side effects.
  • A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

    • Rash
    • Itching or swelling, especially of the face/tongue/throat
    • Severe dizziness
    • Trouble breathing
  • This is not a complete list of possible side effects. If you notice other effects not listed above, request a callback for medical advice. You may also report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Precautions to be aware of
  • Before using Tapinarof, tell your medical provider if you are allergic to it or have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Go to your patient dashboard and request a callback for more details.
  • Before using this medication, tell your medical provider or pharmacist your medical history. 
  • Before having surgery, tell your doctor or dentist about all the products you use, including prescription drugs, nonprescription drugs and herbal products.
  • During pregnancy, this medication should be used only when there is a clear need. Discuss the risks and benefits with your medical provider. 
  • It is unknown if this medication passes into breast milk. Consult your medical provider before breast-feeding.
Drug interactions
  • Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions.
  • Keep a list of all the products you use—including prescription/nonprescription drugs and herbal products—and share it with your medical provider. 
  • Do not start, stop or change the dosage of any medicines without your medical provider's approval.
What to do in the event of an overdose

This medicine may be harmful if swallowed. If someone has overdosed and is experiencing serious symptoms—such as passing out or trouble breathing—call 911. If symptoms from taking this medication are less severe, call your local poison control center at 1-800-222-1222 right away.

Additional notes

Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another skin condition unless your medical provider tells you to.

What to do if you miss a dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

How to store this medication
  • Store at room temperature. Do not freeze. 
  • Keep all medications away from children and pets.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more information.
Treatment for
Generic Name
Tapinarof
Brand
Vtama
Drug Class
Aryl hydrocarbon receptor agonist

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