Get a Roflumilast (Generic Zoryve) prescription online

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Roflumilast is the generic version of Zoryve, a popular psoriasis prescription. Available as a topical cream, this medication is a phosphodiesterase-4 (PDE-4) inhibitor that can help clear patches and reduce inflammation.

* Prescription treatment requires a virtual medical consultation with a medical provider to determine if a prescription is appropriate.

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How Dr. B treats psoriasis

Health assessment

Tell us about your condition with a $15 online consultation—no video call necessary.

Provider review

A medical provider will review your information and prescribe treatment, if appropriate.

Get your medication

Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.

About Roflumilast (Generic Zoryve)

How does it work?

This medication blocks a protein called PDE-4, thought to play a role in inflammation. This medication helps relieve psoriasis symptoms such as rashes, dryness and plaques.

What does it treat?

This medication treats psoriasis, a skin disease characterized by scaly, itchy patches. It improves symptoms by restricting activity of the PDE-4 protein.

What forms does it come in?

This psoriasis treatment is available as a topical cream that you apply to the affected area of skin.

Roflumilast vs. Zoryve

Roflumilast is the active ingredient in the same-named oral and topical psoriasis medicines. The brand medication Zoryve is the topical form. The former is prescribed for COPD and plaque psoriasis, while the latter is usually used just for psoriasis.

More Psoriasis Prescription Treatments

Looking for a different medication? Here are some options.

Common Questions

Roflumilast (Generic Zoryve) prescription FAQ

What are the benefits of using Roflumilast (Generic Zoryve)?
  • Reduces inflammation
  • Encourages healing
  • Eases itching
Who should not use this medication?
  • People who are allergic to it or its ingredients
  • People who have moderate or severe liver disease
  • People who are pregnant or breastfeeding
  • People who are taking certain other medications, including Theophylline or Ketoconazole

If you have any of these conditions, speak with a licensed provider before using this psoriasis treatment.

How do I use this medication?

In most cases, you take the oral tablets once a day with or without food. You apply the cream formulation to the affected areas of skin once a day. Follow your medical provider’s instructions carefully for best results.

What happens if I miss a dose?

If you miss a dose of Roflumilast, take it when you remember. If it’s almost time for the next dose, skip the missed dose and return to your regular schedule. Do not double your dose.

What happens if I use too much?

Taking more of this medication than directed can cause serious side effects such as nausea, vomiting, diarrhea and dizziness.

If you’ve taken too much, call your healthcare provider or local poison control center (800-222-1222) right away.

Can I get Roflumilast (Generic Zoryve) online?

You can access this medication online through a confidential $15 online consultation with Dr. B. A licensed medical provider will review your information and send in an online prescription or refill to your pharmacy of choice if you qualify.

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Dr. Alison Gruen, M.D.Dermatology Advisor

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Side Effects

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Not everyone experiences side effects when prescribed this medication. When they do occur, they’re often mild. Possible side effects include:

  • Diarrhea
  • Nausea
  • Headache
  • Trouble sleeping

If you experience severe side effects like a serious allergic reaction or seizure—or other new and worrying symptoms—contact your health provider or pharmacist immediately.

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