Elidel

Pimecrolimus Elidel is a nonsteroidal topical cream used to treat eczema, also known as atopic dermatitis, by lowering inflammation. The medication's immune-modulating and anti-inflammatory properties can help relieve redness, itchiness and swelling. It is a brand version of the drug Pimecrolimus. Read more about eczema.
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How to use this information  
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective or appropriate for you. This information is not individual medical advice and does not substitute for the advice of a medical provider. If you have any questions, go to your patient dashboard and request a callback for complete information about this product and your specific health needs.
Medication name

PIMECROLIMUS - TOPICAL

(pim-eck-row-LEE-muss)

COMMON BRAND NAME(S): Elidel

Warnings to be aware of
  • Patients have benefited from use of Pimecrolimus when it is used correctly. Long-term safety for this drug is not known at this time. 
  • There have been rare reports of cancers, such as skin cancer and lymphoma, in patients using Pimecrolimus. It is not known whether the medication caused these cancers when used on the skin. Further studies to determine the long-term safety of this product are ongoing. In the unlikely event that unusual lumps, swollen glands or growths (especially on the skin) occur, contact your medical provider right away.
  • The FDA recommends the following: This drug should be used only if other drugs have failed or if other medications are not considered appropriate by your medical provider. Pimecrolimus should be used on the skin for short treatment periods only. 
  • If needed, treatment may be repeated with breaks in between. Use the smallest amount that will treat your condition properly, and apply only on the affected skin. 
  • This medication should not be used by children younger than 2 years. As with all medications, discuss the risks, benefits and proper use of this medication with your medical provider.
What you should know about Pimecrolimus
  • Pimecrolimus is used to treat certain skin conditions such as eczema (atopic dermatitis) in people who should not use or have not responded to other eczema medications like topical steroids. Eczema is an allergic-type condition that causes red, irritated and itchy skin. 
  • This drug works by changing the skin's defense (immune) system, thereby decreasing the allergic reaction that causes eczema. Pimecrolimus belongs to a class of drugs known as topical calcineurin inhibitors (TCIs).
  • This medication is not recommended if you have a history of Netherton's syndrome, a rare genetic disorder. This medication should not be used by anyone who has a weakened immune system—such as patients who have recently undergone an organ transplant.
How to use Pimecrolimus
  • Read the Medication Guide provided by your pharmacist before you start using Pimecrolimus and each time you get a refill. If you have any questions regarding the information, request a callback.
  • Wash your hands with soap and water before using this medication. Apply a thin layer to the affected areas of skin, usually twice daily or as directed by your medical provider. Rub the medication into the skin gently and completely. Wash your hands after using this product, unless your hands are being treated. If your medical provider recommends a moisturizer, apply it after this medication.
  • Pimecrolimus is for use on the skin only. Avoid getting this medication in your eyes or on the inside of your nose or mouth. If you do get the medication in those areas, flush with plenty of water. 
  • Do not apply this medication to open wounds or infected areas. Do not cover the treated area with plastic or waterproof bandages unless directed to do so by your medical provider. Do not bathe, shower or swim right after applying this medication.
  • Use this medication exactly as directed. Your medical provider may instruct you to stop using it once your eczema has cleared up and to start using it again if signs or symptoms reappear. Consult your medical provider for details.
  • Inform your medical provider if your condition does not improve after 6 weeks of using this medication or if your condition worsens at any time.
Potential side effects
  • Mild burning or irritation at the application site may occur during the first few days of treatment. Headache may also occur. If any of these effects last or get worse, tell your medical provider or pharmacist promptly.
  • Remember that this medication has been prescribed because your medical provider has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not experience serious side effects.
  • Tell your medical provider right away if you have any serious side effects, including signs of infection, such as persistent sore throat and fever.
  • A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

    • Rash
    • Itching or swelling, especially of the face/tongue/throat
    • Severe dizziness
    • Trouble breathing
  • This is not a complete list of possible side effects. If you notice other effects not listed above, request a callback for medical advice. You may also report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

Precautions to be aware of
  • Before using Pimecrolimus, tell your medical provider or pharmacist if you are allergic to it or have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Request a callback for more details.
  • Before using this medication, tell your medical provider or pharmacist your medical history, especially of:

    • Current infections like mononucleosis
    • Use of light therapy, such as UVA or UVB
    • Skin infections, such as herpes, chickenpox, shingles or warts
    • Immune system problems.
  • This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your medical provider right away if you get sunburned or have skin blisters/redness.
  • During pregnancy, this medication should be used only when there is a clear need. Discuss the risks and benefits with your medical provider.
  • It is unknown if this medication passes into breast milk. Consult your medical provider before breastfeeding.
Drug interactions
  • Drug interactions may change how your medications work or increase your risk for serious side effects.
  • This document does not contain all possible drug interactions. Keep a list of all the products you use—including prescription/nonprescription drugs and herbal products—and share it with your medical provider and pharmacist. 
  • Do not start, stop or change the dosage of any medicines without your medical provider's approval.  
  • Some products that may interact with this drug are topical steroids and other ointments/lotions/creams.
What to do in the event of an overdose

If someone has overdosed and has serious symptoms, such as passing out or trouble breathing, call 911. If symptoms from taking this medication are less severe, call your local poison control center at 1-800-222-1222 right away.

Additional notes
  • Do not share this medication with others. 
  • This drug should be used as directed for treating your current condition only. Do not use it later for another condition unless told to do so by your medical provider. A different medication may be necessary in that case.
  • Keep all medical appointments while you are using this medication.
What to do if you miss a dose
  • If you miss a dose, use it as soon as you remember.
  • If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. 
  • Do not double the dose to catch up.
How to store this medication
  • Store at room temperature away from light and moisture. Do not freeze. 
  • Make sure the cap on the tube is tightly closed. Keep all medications away from children and pets.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Treatment for
Generic Name
Pimecrolimus
Brand
Elidel
Drug Class
Immunosuppressant

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