Glycopyrronium Tosylate Qbrexza topical wipes are used to treat hyperhidrosis (excessive sweating). Qbrexza is a brand version of Glycopyrronium Tosylate, an anticholinergic that blocks neurotransmitters from communicating with the nervous system. When applied to the armpits, these wipes help reduce sweating. Read more about hyperhidrosis.
Start Consultation*Prescription treatment requires a virtual medical consultation with a medical provider to determine if a prescription is appropriate.
How to use this information
This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective or appropriate for you. This information is not individual medical advice and does not substitute for the advice of a medical provider. If you have any questions, go to your patient dashboard and request a callback for complete information about this product and your specific health needs.
Medication name
What you should know about Glycopyrronium cloth

This form of Glycopyrronium is used to treat excessive sweating from the underarms. The drug solution is infused into a damp cloth that can be applied to the skin. Glycopyrronium blocks ACh neurotransmitters from communicating with the central and peripheral nervous systems, thereby reducing sweat glands activity. Glycopyrronium belongs to a class of drugs known as anticholinergics, a neurotransmitter inhibitor.

How to use Glycopyrronium cloth
  • Read the Patient Information Leaflet if available from your pharmacist before you start using this product and each time you get a refill. If you have any questions, request a callback from your medical provider.
  • Use as directed by your medical provider, usually once daily. Apply only to clean, dry skin of your underarms. Do not apply to broken skin.
  • To use, carefully open one pouch and remove the cloth. Unfold the cloth and apply by wiping once across one underarm. Using the same cloth, wipe once across the other underarm.
  • Do not cover the treated area(s) with a plastic dressing or bandage.
  • Do not save the cloth to use again. Throw away the used cloth in the trash.
  • To avoid accidentally getting this medication in your eyes or other areas, wash your hands right away with soap and water after using the cloth.
  • Use this product regularly to get the most benefit from it. To help you remember, use it at the same time each day. Tell your medical provider if your condition continues or worsens.
Potential side effects
  • Redness, burning, stinging or itching at the application site may occur. Dry mouth/nose/throat, dry skin, headache or blurred vision may also occur. If any of these effects last or get worse, request a callback from your medical provider promptly.
  • This medication has been prescribed because your medical provider has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
  • Request a callback from your medical provider right away if you have any serious side effects, including: trouble urinating (such as weak stream or drips, urinating very often, full bladder).
  • A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness or trouble breathing.
  • This is not a complete list of possible side effects. If you notice other effects not listed above, request a callback for medical advice. You may also report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
Precautions to be aware of
  • Before using Glycopyrronium, tell your medical provider if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Request a callback from your medical provider for more details.
  • Before using this medication, tell your medical provider about your medical history, especially if it includes: glaucoma, myasthenia gravis, Sjogren's syndrome, stomach/intestinal problems (such as slow gut, blockage, ulcerative colitis), trouble urinating (such as due to enlarged prostate, bladder problems) or kidney problems.
  • This drug may cause temporary blurred vision. Do not drive, use machinery or do anything that needs clear vision until you can do it safely.
  • This medication may make your body sweat less in areas other than your underarms. This effect may make you more likely to get heat stroke in very warm or hot weather. If you notice you are not sweating on your body in these conditions, stop using this product. If you overheat, quickly look for a place to cool down and rest.
  • Get medical help right away if you have a fever that does not go away, mental/mood changes, fast/weak heartbeat or dizziness.
  • Before having surgery, tell your specialist or dentist about all the products you use (including prescription drugs, nonprescription drugs and herbal products).
  • Tell your OB-GYN if you are pregnant before using this product.
  • It is unknown if this medication passes into breast milk. Consult your OB-GYN before breast-feeding.
Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your medical provider. Do not start, stop or change the dosage of any medicines without your medical provider's approval.

What to do in the event of an overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. If symptoms from taking this medication are less severe, call your local poison control center at 1-800-222-1222 right away.

Additional notes

Do not share this medication with others.

What to do if you miss a dose

If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

How to store this medication
  • Store at room temperature away from light and moisture.
  • This medication is flammable, so keep it away from heat and open flame. 
  • Keep all medications away from children and pets.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Treatment for
Generic Name
Glycopyrronium Tosylate
Drug Class
Anticholinergics Topical

What is Dr. B?

At Dr. B, you can get convenient medical care—including prescription treatments—right from home. We believe everyone deserves affordable access to healthcare. That's why an online consultation with a licensed provider is only $15. Need more financial support? Dr. B also offers a No-Cost Care* option for those who qualify.

* Financial hardship assistance available for those who qualify

Send your prescription anywhere

Walgreens logo Amazon logo Walmart logo CVS logo

Send your prescription to thousands of pharmacies for pickup or online delivery. Your choice.

Young woman wearing blue blouse and a purse, looking down at her phone and about to tap on it

How Dr. B treats hyperhidrosis

Health assessment

Tell us about your condition with a $15 online consultation—no video call necessary.

Provider review

A medical provider will review your information and prescribe treatment, if appropriate.

Get your medication

Pick up and pay for the medication at the pharmacy of your choice. Or, get it delivered.

More hyperhidrosis Options

“The process could not have been easier. My chart was reviewed by a licensed professional and I was able to pick up my prescription at my preferred local pharmacy within a few hours.”

Meghan E. from Florida

Verified Patient

“Dr. B made it easy and affordable to get my medication. I was able to get a prescription without having to go through the hassle of having to make a doctor’s appointment, take time off work, etc., all while knowing that there is a trusted medical professional taking care of me.”

Marsha D. from Florida

Verified Patient

“The process for the Dr. B birth control was very easy and efficient. The website made getting prescription birth control easily accessible, especially for someone like me who does not have an established primary doctor in the area yet.”

Jennifer F. from Florida

Verified Patient

Featured On

The New York Times logo
Axios logo
TIME logo
Bloomberg logo
Fast Company logo
ABC logo